How dare you ship Spuffy! You liked the handcuffs, didn't you?
I personally like Buffy and Angel better even though they never got their happily ever after. Buffy and Spike were fine up until mid-Season 6. It just got too dysfunctional after that. Their scenes in Season 7 were good though. I liked the "I know I'm a monster, but you treat me like a man" line from Season 5. No, I'm not obsessed with that show at all...
And to add to the list:
Luke and Lorelai from Gilmore Girls (who should have gotten married!)
Archie and Betty
Meredith and Derek from Grey's Anatomy "Pick me, choose me, love me."