My Mom used the terms muddleheaded, drunk and three sheets to the wind to describe the level of inebriation of a person.

Then there Patsy and Edina who are off the charts.

Can anyone remember what muddleheaded thing they did to end up drinking champagne on a garbage scow?

Actually, I haven't heard this term used since I was growing up.  My grandparents would use the word to describe anyone they didn't agree with.  

Today the 98 degree (38.7 C) heat and humidity left me a little muddleheaded. That's not unusual for Mississippi in July, but it is brutal. You have to watch out for old folks, kids and pets.