Ecstacy, or MDMA, (a.k.a. E, or Molly) is a popular party drug that was created and used to facilitate psychotherapy. First synthesized by a German chemist in 1912, it became a popular street drug in the seventies. The US FDA made it a Schedule 1 narcotic. As of 2021, there were limited studies of its use to treat the anxiety and depression accompany PTSD. Users of MDMA get a happy, euphoric, friendly, and silly high.

It is a complex drug to synthesize, and small errors in the process can create dangerous isomers of the basic compound. In the eighties, a bad batch was released nationwide, which caused the symptoms of early onset Parkinson's disease. Others have the opposite effect, and make the user angry and belligerent.