The word "concoction" comes from the Latin verb concoquere, meaning "to cook together". from the prefix con- ("together") and coquere ("to cook").  It originally referred to the act of cooking, mixing, or digesting ingredients, or to purifying metals by heating them. Over time, its meaning expanded to include any mixture or a cleverly invented story or scheme.  The earliest use of the word concoction referred to the literal cooking and mixing of ingredients, such as in food or medicine.  The extended meaning is the sense of "making by mixing" evolved into "making up" in a more figurative sense, leading to the modern use of "concoction" for something invented, like a story or an excuse. 

 According to the Oxford English Dictionary (OED), the noun concoction was first used in English in 1531 in the writings of the diplomat and humanist Thomas Elyot. 

Examples of "concoction" used in a sentence: 
"The keirin is a strange concoction of speed, tactics and nerve." 
"The secret is a wondrous concoction of red jalapeno chili peppers, vinegar, garlic, sugar and salt." 
"I used to make a thick, sweet concoction of honey, yogurt, oats, and apples." 
"After 5 p.m., the space shifts from cozy teahouse to experimental mixology bar, serving boozy concoctions that all feature tea as an ingredient." 
"The treat is so beloved that Somerville is home to an annual What the Fluff? festival, where tens of thousands of people celebrate every possible use of the concoction, a mixture of corn syrup, sugar, egg white and vanillin." (according to The New York Times)

A common and expensive concoction is the cocktail. It also happens to be a serious intoxicant.

3 minutes ago, drpaladin said:

A Duck Fart Shot is serious?

OK I'm an Aussie. I'd never heard of a Duck Fart Shot and had to google it. While i admired the skill in making it, I still wasn't tempted to rush out and try it, that's assuming I could find local a bar serving it. No the concoction I'll stick to tonight is a Syrah Sangiovense blend. A lovely red wine.