The word "wizened" comes from Old English wisnian, meaning "to wither, dry up, or waste away."  This Old English verb is related to the Proto-Germanic *wisnōjaną, which also means "to wither".  The adjective "wizened" evolved from the past participle of this verb, and appears in English from the early 1500s. While the verb "wizen" is now largely obsolete, the adjective "wizened" persists in English to describe someone or something that is shriveled or wrinkled with age. 

The adjective "wizened" first appeared in the English language in the early 1500s.  The Oxford English Dictionary cites a translation by Gavin Douglas in 1513 as the earliest known use.  Douglas was a poet and the bishop of Dunkeld in Scotland.  The word is derived from the verb "wizen," which itself has a longer history in English, going back to Old English around the late 800s. 

Examples of "wizened" in a sentence:  
"His wrinkles overlapped his pox scars, giving him a wizened wizard look." 
"He shook his head, his gaze taking on a wizened look." 
"Instead we looked on at a wizened old man spinning stories." 
"His wizened face creased with emotions and he did not stop the tears coursing down as he introduced me to his family." 
"I felt that I had been abandoned to these strange people with their black robes and wizened old faces!" 
"Standing by a row of hand basins was a little wizened old lady." 

Just the facts:

WIZEN Definition & Meaning - Merriam-Webster

WIZENED | English meaning - Cambridge Dictionary

Wizened - Definition, Meaning & Synonyms | Vocabulary.com